Our chief area of interest involves the design of highly inducible eukaryotic expression vectors for the production and study of potentially cytotoxic proteins in animals and in stably transformed cell lines. Transcription, translation, and mRNA turnover signals are being combined in a shuttle vector so as to confer tissue specificity and to maximize the speed, the range of induction, and the induced steady state level of virtually any protein.

• Selected Publications

Induction of rabbit transgene by iron in human cells. (Human H and L Ferritin were also induced.)